研究概要

主要論文

「*」は、理研外のみでの成果です。

• 1. Yazaki J, Yamanashi T, Nemoto S, Kobayashi A, Han YW, Hasegawa T, Iwase A, Ishikawa M, Konno R, Imami K, Kawashima Y, Seita J.:
  "Mapping adipocyte interactome networks by HaloTag-enrichment-mass spectrometry."
  Biol Methods Protoc. 29;9(1):bpae039 (2024)
• 2. Ohta T, Hananoe A, Fukushima-Nomura A, Ashizaki K, Sekita A, Seita J, Kawakami E, Sakurada K, Amagai M, Koseki H, Kawasaki H.:
  "Best practices for multimodal clinical data management and integration: An atopic dermatitis research case."
  Allergol Int. 73(2):255-263. (2024)
• 3. Sekita A, Kawasaki H, Fukushima-Nomura A, Yashiro K, Tanese K, Toshima S, Ashizaki K, Miyai T, Yazaki J, Kobayashi A, Namba S, Naito T, Wang QS, Kawakami E, Seita J, Ohara O, Sakurada K, Okada Y, Amagai M, Koseki H.:
  "Multifaceted analysis of cross-tissue transcriptomes reveals phenotype-endotype associations in atopic dermatitis."
  Nat Commun. 2;14(1):6133. (2023)
• 4. Kobayashi M, Wei H, Yamanashi T, Azevedo Portilho N, Cornelius S, Valiente N, Nishida C, Cheng H, Latorre A, Zheng WJ, Kang J, Seita J, Shih DJ, Wu JQ, Yoshimoto M.:
  "HSC-independent definitive hematopoiesis persists into adult life."
  Cell Rep. 28;42(3):112239. (2023)
• 5. Sato Y, Oguchi A, Fukushima Y, Masuda K, Toriu N, Taniguchi K, Yoshikawa T, Cui X, Kondo M, Hosoi T, Komidori S, Shimizu Y, Fujita H, Jiang L, Kong Y, Yamanashi T, Seita J, Yamamoto T, Toyokuni S, Hamazaki Y, Hattori M, Yoshikai Y, Boor P, Floege J, Kawamoto H, Murakawa Y, Minato N, Yanagita M.:
  "CD153/CD30 signaling promotes age-dependent tertiary lymphoid tissue expansion and kidney injury."
  J Clin Invest. 132(2):e146071. (2022)
• 6. *Travaglini KJ, Nabhan AN, Penland L, Sinha R, Gillich A, Sit RV, Chang S, Conley SD, Mori Y, Seita J, Berry GJ, Shrager JB, Metzger RJ, Kuo CS, Neff N, Weissman IL, Quake SQ, Krasnow MA.:
  "A molecular cell atlas of the human lung from single cell RNA sequencing"
  Nature 587(7835):619 (2020)
• 7. Yazaki J, Kawashima Y, Ogawa T, Kobayashi A, Okoshi M, Watanabe T, Yoshida S, Kii I, Egami S, Amagai M, Hosoya T, Shiroguchi K, Ohara O.:
  "HaloTag-based conjugation of proteins to barcoding-oligonucleotides"
  Nucleic Acids Res. 48(2):e8 (2020)
• 8. Kawashima Y, Watanabe E, Umeyama T, Nakajima D, Hattori M, Honda K, Ohara O.:
  "Optimization of Data-Independent Acquisition Mass Spectrometry for Deep and Highly Sensitive Proteomic Analysis"
  Int J Mol Sci. 20(23) 5932 (2019)
• 9. Kawashima Y, Miyata J, Watanabe T, Shioya J, Arita M, Ohara O.:
  "Proteogenomic Analyses of Cellular Lysates Using a Phenol-Guanidinium Thiocyanate Reagent"
  J Proteome Res. 18(1), 301-308 (2019)
• 10. Rosental B, Kowarsky M, Seita J, Corey DM, Ishizuka KJ, Palmeri KJ, Chen SY, Sinha R, Okamoto J, Mantalas G, Manni L, Raveh T, Clarke DN, Tsai JM, Newman AM, Neff NF, Nolan GP, Quake SR, Weissman IL, Voskoboynik A.:
  "Complex mammalian-like haematopoietic system found in a colonial chordate"
  Nature. 564(7736) 425 (2018)

研究成果（プレスリリース）

• 

  2025年10月7日
  ストレスタイプが決定する老化とがん化の分岐点とその仕組み

• 

  2024年11月19日
  モノクローナル抗体の新スクリーニング法を開発

• 

  2019年11月29日
  DNAバーコーディングによるタンパク質のデジタル定量法

関連リンク

メンバーリスト

採用情報

募集職種	応募締切
上級研究員、研究員または特別研究員募集（25-1550）	ポストが決まり次第

お問い合わせ先