Research Summary

Selected Publications

Papers with an asterisk(*) are based on research conducted outside of RIKEN.

• 1. *Ling E §, Nemesh J, Goldman M, Kamitaki N, Reed N, Handsaker RE, Genovese G, Vogelgsang JS, Gerges S, Kashin S, Ghosh S, Esposito JM, Morris K, Meyer D, Lutservitz A, Mullally CD, Wysoker A, Spina L, Neumann A, Hogan M, Ichihara K, Berretta S §#, McCarroll SA §#. (§ = co-corresponding author; # = co-senior author)
  "A concerted neuron-astrocyte program declines in ageing and schizophrenia."
  Nature 627:604-611 (2024).
  doi: 10.1038/s41586-024-07109-5
• 2. *Yang MG ^, Ling E ^, Cowley CJ, Greenberg ME §, Vierbuchen T §. (^ = co-first author; § = co-corresponding author)
  "Characterization of sequence determinants of enhancer function using natural genetic variation."
  eLife 11:e76500 (2022).
  doi: 10.7554/eLife.76500
• 3. *Ford L ^, Ling E ^, Kandel ER §, Fioriti L §. (^ = co-first author; § = co-corresponding author)
  "CPEB3 inhibits translation of mRNA targets by localizing them to P bodies."
  PNAS 116:18078-18087 (2019).
  doi: 10.1073/pnas.1815275116
• 4. *Vierbuchen T ^§, Ling E ^, Cowley CJ, Couch CH, Wang X, Harmin DA, Roberts CWM, Greenberg ME. (^ = co-first author; § = corresponding author)
  "AP-1 Transcription Factors and the BAF Complex Mediate Signal-Dependent Enhancer Selection."
  Molecular Cell 68:1067-1082 (2017).
  doi: 10.1016/j.molcel.2017.11.026
• 5. *Yang S, Datta D, Krienen FM, Woo E, May A, Anderson GM, Galvin VC, Gonzalez-Burgos G, Lewis DA, Ling E, McCarroll SA, Arnsten AF, Wang M.
  "Kynurenic acid signaling expands in human and nonhuman primates and impairs dorsolateral prefrontal cortical cognition that is key to mental illness."
  Mol Psychiatry 31:1190-1200 (2026).
  doi: 10.1038/s41380-025-03425-y
• 6. *Datta D, Yang S, Joyce MKP, Woo E, McCarroll SA, Gonzalez-Burgos G, Perone I, Uchendu S, Ling E, Goldman M, Berretta S, Murray J, Morozov Y, Arellano J, Duque A, Rakic P, O'Dell R, van Dyck CH, Lewis DA, Wang M, Krienen FM §, Arnsten AFT §. (§ = co-corresponding author)
  "Key Roles of CACNA1C/Cav1.2 and CALB1/Calbindin in Prefrontal Neurons Altered in Cognitive Disorders."
  JAMA Psychiatry 81:870-881 (2024).
  doi: 10.1001/jamapsychiatry.2024.1112
• 7. *Pollina EA ^, Gilliam DT ^, Landau AT, Lin C, Pajarillo N, Davis CP, Harmin DA, Yap EL, Vogel IR, Griffith EC, Nagy MA, Ling E, Duffy EE, Sabatini BL, Weitz CJ, Greenberg ME. (^ = co-first author)
  "A NPAS4-NuA4 complex couples synaptic activity to DNA repair."
  Nature 614:732-741 (2023).
  doi: 10.1038/s41586-023-05711-7
• 8. *Weiner DJ §, Ling E, Erdin S, Tai DJC, Yadav R, Grove J, Fu JM, Nadig A, Carey CE, Baya N, Bybjerg-Grauholm J, Berretta S, Macosko EZ, Sebat J, O'Connor LJ, Hougaard DM, Børglum AD, Talkowski ME, McCarroll SA, Robinson EB §. (§ = co-corresponding author)
  "Statistical and functional convergence of common and rare genetic influences on autism at chromosome 16p."
  Nat Genet 54:1630-1639 (2022).
  doi: 10.1038/s41588-022-01203-y
• 9. *Stroud H, Yang MG, Tsitohay YN, Davis CP, Sherman MA, Hrvatin S, Ling E, Greenberg ME.
  "An Activity-Mediated Transition in Transcription in Early Postnatal Neurons."
  Neuron 107:874-890.e8 (2020).
  doi: 10.1016/j.neuron.2020.06.008
• 10. *Cheadle L ^, Tzeng CP ^, Kalish BT, Harmin DA, Rivera S, Ling E, Nagy MA, Hrvatin S, Hu L, Stroud H, Burkly LC, Chen C, Greenberg ME. (^ = co-first author)
  "Visual Experience-Dependent Expression of Fn14 Is Required for Retinogeniculate Refinement."
  Neuron 99:525-539.e10 (2018).
  doi: 10.1016/j.neuron.2018.06.036

Lab Members

Careers

Position	Deadline
Seeking Research Scientist or Postdoctoral Researcher (26-201)	Open until filled
Seeking a Technical Staff I (26-177)	Open until filled

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