Research Summary

Selected Publications

• 1.Ngou BPM, Wyler M, Schmid MW, Suzuki T, Albert M, Dohmae N, Kadota Y, Shirasu K.
  "Systematic discovery and engineering of synthetic immune receptors in plants."
  Science. 389(6764):eadx2508 (2025)
• 2.Kato K, Kumazawa M, Nakajima Y, Suzuki T, Dohmae N, Shen JR, Ifuku K, Nagao R.
  "Structure of a photosystem I supercomplex from Galdieria sulphuraria close to an ancestral red alga."
  Sci. Adv. 11(20):eadv7488 (2025)
• 3.Yoshida Y, Takahashi T, Ishii N, Matsuo I, Takahashi S, Inoue H, Endo A, Tsuchiya H, Okada M, Ando C, Suzuki T, Dohmae N, Saeki Y, Tanaka K, Suzuki T.
  "Sugar-mediated non-canonical ubiquitination impairs Nrf1/NFE2L1 activation."
  Mol. Cell. 84(16):3115-3127.e11 (2024)
• 4.Nishiyama K, Aihara Y, Suzuki T, Takahashi K, Kinoshita T, Dohmae N, Sato A, Hagihara S.
  "Discovery of a Plant 14-3-3 Inhibitor Possessing Isoform Selectivity and In Planta Activity."
  Angew. Chem. Int. Ed. Engl. 63(27):e202400218 (2024)
• 5.Yamagata A, Ito K, Suzuki T, Dohmae N, Terada T, Shirouzu M.
  "Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A"
  Nat. Commun. 15(1):3027 (2024)
• 6.Kaizuka T, Suzuki T, Kishi N, Tamada K, Kilimann MW, Ueyama T, Watanabe M, Shimogori T, Okano H, Dohmae N, Takumi T.
  "Remodeling of the postsynaptic proteome in male mice and marmosets during synapse development"
  Nat. Commun. 15(1):2496 (2024)
• 7.Kato K, Hamaguchi T, Kumazawa M, Nakajima Y, Ifuku K, Hirooka S, Hirose Y, Miyagishima SY, Suzuki T, Kawakami K, Dohmae N, Yonekura K, Shen JR, Nagao R.
  "The structure of PSI-LHCI from Cyanidium caldarium provides evolutionary insights into conservation and diversity of red-lineage LHCs."
  Proc. Natl. Acad. Sci. USA. 121(11):e2319658121.5 (2024)
• 8.Chiba Y, Ooka H, Wintzer ME, Tsunematsu N, Nogawa T, Suzuki T, Dohmae N, Nakamura R.
  "Rationalizing the Influence of the Binding Affinity on the Activity of Phosphoserine Phosphatases."
  Angew. Chem. Int. Ed. Engl. 63(13):e202318635 (2024)
• 9.Kuchitsu Y, Mukai K, Uematsu R, Takaada Y, Shinojima A, Shindo R, Shoji T, Hamano S, Ogawa E, Sato R, Miyake K, Kato A, Kawaguchi Y, Nishitani-Isa M, Izawa K, Nishikomori R, Yasumi T, Suzuki T, Dohmae N, Uemura T, Barber GN, Arai H, Waguri S, Taguchi T.
  "STING signalling is terminated through ESCRT-dependent microautophagy of vesicles originating from recycling endosomes"
  Nat. Cell Biol. 25(3):453-466 (2023)
• 10.Nakagawa R, Hirano H, Omura SN, Nety S, Kannan S, Altae-Tran H, Yao X, Sakaguchi Y, Ohira T, Wu WY, Nakayama H, Shuto Y, Tanaka T, Sano FK, Kusakizako T, Kise Y, Itoh Y, Dohmae N, van der Oost J, Suzuki T, Zhang F, Nureki O.
  "Cryo-EM structure of the transposon-associated TnpB enzyme."
  Nature. 616(7956):390-397 (2023)

Recent Research Results

• 

  Apr. 5, 2018
  Newly discovered hormone helps keep plants from dehydrating

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